| Team | W | L |
| 49ers | 13 | 3 |
| Cardinals | 8 | 8 |
| Seahawks | 7 | 9 |
| Rams | 2 | 14 |
| Pre | |||
| 12-Aug | @Saints | L | 3-24 |
| 20-Aug | Raiders | W | 17-3 |
| 27-Aug | Texans | L | 7-30 |
| 1-Sep | @Chargers | W | 20-17 |
| Reg | |||
| 11-Sep | Seahawks | W | 33-17 |
| 18-Sep | Cowboys | L | 24-27 |
| 25-Sep | @Bengals | W | 13-8 |
| 2-Oct | @Eagles | W | 24-23 |
| 9-Oct | Buccaneers | W | 48-3 |
| 16-Oct | @Lions | W | 25-19 |
| 30-Oct | Browns | W | 20-10 |
| 6-Nov | @Redskins | W | 19-11 |
| 13-Nov | Giants | W | 27-20 |
| 20-Nov | Cardinals | W | 23-7 |
| 24-Nov | @Ravens | L | 6-16 |
| 4-Dec | Rams | W | 26-0 |
| 11-Dec | @Cardinals | L | 19-21 |
| 19-Dec | Steelers | W | 20-3 |
| 24-Dec | @Seahawks | W | 19-17 |
| 1-Jan | @Rams | W | 34-27 |
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