| Team | W | L | T | Streak |
| Cardinals | 10 | 6 | 0 | W1 |
| 49ers | 8 | 8 | 0 | L1 |
| Seahawks | 5 | 11 | 0 | W2 |
| Rams | 1 | 15 | 0 | L4 |
| Schedule 2010 | |||||
| WK | Date | Opp | Result | ||
| 1 | 9/12 | @ Sea | |||
| 2 | 9/20 | vs. NO | |||
| 3 | 9/26 | @ KC | |||
| 4 | 10/3 | @ Atl | |||
| 5 | 10/10 | vs. Phi | |||
| 6 | 10/17 | vs. Oak | |||
| 7 | 10/24 | @ Car | |||
| 8 | 10/31 | vs. Den | |||
| 9 | Bye Week | ||||
| 10 | 11/14 | vs. StL | |||
| 11 | 11/21 | vs. TB | |||
| 12 | 11/29 | @ Ari | |||
| 13 | 12/5 | @ GB | |||
| 14 | 12/12 | vs. Sea | |||
| 15 | 12/16 | @ SD | |||
| 16 | 12/26 | @ StL | |||
| 17 | 1/2 | vs. Ari | |||
| Name | Pos. | Signed | 2007 Salary | SB | Base |
| Staley, Joe | LT | 2017 | $1,020,000 | $220,000 | $285,000 |
| Willis, Patrick | RILB | 2016 | $2,685,000 | $2,400,000 | $285,000 |
| Iupati, Mike | OG | 2014 | $0 | $0 | $0 |
| Jennings, Brian | LS | 2014 | $903,333 | $183,333 | $720,000 |
| Davis, Anthony | RT | 2014 | $0 | $0 | $0 |
| Mays, Taylor | SS | 2013 | $0 | $0 | $0 |
| Williams, Kyle | WR | 2013 | $0 | $0 | $0 |
| Clements, Nate | LCB | 2013 | $8,388,607 | $0 | $600,000 |
| Brown, Tarell | RCB | 2013 | $328,000 | $43,000 | $285,000 |
| Smith, Justin | DE | 2013 | $0 | $0 | $0 |
| Adams, Phillip | CB | 2013 | $0 | $0 | $0 |
| Byham, Nate | TE | 2013 | $0 | $0 | $0 |
| Haralson, Parys | ROLB | 2013 | $404,000 | $44,000 | $360,000 |
| Bowman, Navorro | ILB | 2013 | $0 | $0 | $0 |
| Dixon, Anthony | RB | 2013 | $0 | $0 | $0 |
| Crabtree, Michael | WR | 2013 | $0 | $0 | $0 |
| Davis, Nate | QB | 2012 | $0 | $0 | $0 |
| Taylor, Curtis | FS | 2012 | $0 | $0 | $0 |
| Lee, Andy | P | 2012 | $876,666 | $276,666 | $600,000 |
| McKillop, Scott | ILB | 2012 | $0 | $0 | $0 |
| Jean-Francois, Ricky | NT | 2012 | $0 | $0 | $0 |
| Sopoaga, Isaac | DE | 2012 | $569,500 | $109,500 | $460,000 |
| Spencer, Shawntae | CB | 2012 | $3,010,000 | $0 | $510,000 |
| Walker, Delanie | TE | 2012 | $385,500 | $25,500 | $360,000 |
| Boone, Alex | RT | 2011 | $0 | $0 | $0 |
| Nedney, Joe | PK | 2011 | $1,397,500 | $390,000 | $1,007,500 |
| Burnett, Martail | OLB | 2011 | $0 | $0 | $0 |
| Snyder, Adam | OG | 2011 | $1,386,833 | $951,833 | $435,000 |
| Heitmann, Eric | C | 2011 | $1,360,000 | $325,000 | $1,035,000 |
| Brooks, Ahmad | OLB | 2011 | $0 | $0 | $0 |
| Rachal, Chilo | RG | 2011 | $0 | $0 | $0 |
| Morgan, Josh | WR | 2011 | $0 | $0 | $0 |
| Ginn Jr., Ted | WR | 2011 | $0 | $0 | $0 |
| Carr, David | QB | 2011 | $0 | $0 | $0 |
| Gore, Frank | RB | 2011 | $1,924,835 | $1,489,835 | $435,000 |
| Zeigler, Dominique | WR | 2011 | $79,900 | $0 | $79,900 |
| Norris, Moran | FB | 2011 | $1,000,000 | $305,000 | $695,000 |
| Brock, Tramaine | CB | 2011 | $0 | $0 | $0 |
| Smith, Reggie | SS | 2011 | $0 | $0 | $0 |
| James, William | CB | 2010 | $0 | $0 | $0 |
| Paymah, Karl | CB | 2010 | $0 | $0 | $0 |
| Brown, Jarrett | QB | 2010 | $0 | $0 | $0 |
| LaBoy, Travis | OLB | 2010 | $0 | $0 | $0 |
| Long, Brandon | OLB | 2010 | $0 | $0 | $0 |
| Westbrook, Brian | RB | 2010 | $0 | $0 | $0 |
| Patrick, Chris | OT | 2010 | $0 | $0 | $0 |
| Lawson, Manny | LOLB | 2010 | $1,412,500 | $1,052,500 | $360,000 |
| Smith, Alex | QB | 2010 | $7,535,000 | $5,860,000 | $1,675,000 |
| Wragge, Tony | C | 2010 | $600,000 | $0 | $510,000 |
| Lewis, Michael | SS | 2010 | $4,195,000 | $0 | $595,000 |
| Franklin, Aubrayo | NT | 2010 | $1,416,666 | $766,666 | $650,000 |
| McDonald, Ray | DE | 2010 | $428,125 | $143,125 | $285,000 |
| Spikes, Takeo | ILB | 2010 | $0 | $0 | $0 |
| Sims, Barry | RT | 2010 | $0 | $0 | $0 |
| Baas, David | C/ OG | 2010 | $849,375 | $400,000 | $449,375 |
| Evans, Demetric | DE | 2010 | $0 | $0 | $0 |
| Briggs, Diyral | OLB | 2010 | $0 | $0 | $0 |
| Goldson, Dashon | FS | 2010 | $388,250 | $103,250 | $285,000 |
| Davis, Vernon | TE | 2010 | $2,800,000 | $2,440,000 | $360,000 |
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